Amazon RDS provides AI-powered monitoring and optimization through Performance Insights and DevOps Guru integration. Performance Insights analyzes database load using wait events methodology—identifying what queries are waiting for rather than just execution time. Free tier includes 7 days history and 1M API requests/month; paid tier at $1.50/vCPU/month extends to 2 years history. Supports RDS for PostgreSQL, MySQL, MariaDB, Oracle, and SQL Server. DevOps Guru for RDS adds ML-powered anomaly detection, proactive insights predicting issues before impact, and recommended remediation actions. The service identifies unusual patterns like connection spikes, memory pressure, and storage exhaustion before they cause outages. IMPORTANT: Performance Insights console ending June 30, 2026—transitioning to CloudWatch Database Insights which combines RDS metrics with broader observability. Page should cover: Performance Insights setup and interpretation, wait event analysis methodology, DevOps Guru configuration, free vs paid tier comparison, CloudWatch Database Insights migration guide, supported RDS engines, and comparison with third-party monitoring.